The best way to clean acrylic is with a specialty cleaning product such as Novus. NEVER use window cleaning fluids with ammonia (such as Windex or Formula 409), gasoline, denatured alcohol, carbon tetrachloride, or acetone, which will cause the acrylic to craze with minute cracks. A mild solution of soap or detergent and water can also be used safely. Begin by gently blowing away any loose dust or dirt from the acrylic’s surface. Apply the specialty cleaning product (or soap and water solution) with a dampened non-abrasive/non-contaminating/lint-free soft cloth, microfiber cloth or cellulose sponge. Rinse well with clear, clean water. Blot dry with a chamois, damp cellulose sponge or microfiber cloth to prevent water spotting.
Note: Grease, oil and tar may be removed with a good grade of hexane, naptha or kerosene. Be sure to wash these solvents off quickly to prevent damage to the acrylic